Skinbetter Science InterFuse Intensive Treatment LINES

$210.00

A no-needle, targeted hyaluronic acid treatment designed to visibly plump and soften deep expression lines, including smile lines, crow's feet, forehead lines and lines around the mouth. Powered by skinbetter's patented InterFuse delivery technology, it features five types of hyaluronic acid, including injectable-grade HA, to help re-volumize the look of skin.

Pairs well with: InterFuse Treatment Cream FACE & NECK and InterFuse Treatment Cream EYE for amplified results.

How to use: Apply morning and evening to clean, dry skin, focusing on areas of concern, before your moisturizer. Use sunscreen during the day.

Size: 15 ml / 0.5 fl. oz.

LINES is the product we recommend when someone points at a specific line and says "this one." It's targeted, it's concentrated, and it gives that softened, plumped look without a needle.

It's also a great in-between option for clients who get injectables but want to stretch the time between appointments, or for anyone who isn't ready for fillers yet. A small tube goes a long way.

InterFuse Intensive Treatment LINES is Skinbetter Science's no-needle answer to deep expression lines. This targeted topical treatment uses five types of hyaluronic acid, including injectable-grade, high molecular weight HA, to visibly re-volumize and plump areas where lines have set in: smile lines, crow's feet, forehead lines and lines around the mouth.

Large HA molecules normally struggle to penetrate skin. Skinbetter's patented InterFuse Technology surrounds them with a lipid coating and temporarily relaxes the skin's surface tension so these high-performance ingredients can be delivered where they're needed.

With consistent twice-daily use, lines look softer and shallower and skin looks smoother and more supple. It's designed to pair with InterFuse Treatment Cream FACE & NECK; used together in clinical testing, the duo delivered an average 50% improvement in the appearance of facial skin texture at week 8.

Apply morning and evening to clean, dry skin.

Smooth a small amount directly onto areas of concern (smile lines, crow's feet, forehead, upper lip), or apply over the full face and neck.

Follow with InterFuse Treatment Cream FACE & NECK or your moisturizer, and protect with SPF during the day.

InterFuse Technology
A patented delivery system that coats large molecules in modified essential fatty acids and temporarily relaxes surface tension so they can be delivered into the skin.

Five Types of Hyaluronic Acid
Including injectable-grade, high molecular weight HA, to visibly re-volumize and plump the appearance of deep expression lines and wrinkles.

Formulated without parabens, fragrance or dyes. Dermatologist tested.

Frequently Asked Questions

The best anti-aging treatment for deep facial lines depends on whether you want at-home skincare or in-office procedures, but for topical care, a targeted line treatment with hyaluronic acid is one of the most effective choices for visibly plumping expression lines. Skinbetter Science InterFuse Intensive Treatment LINES is designed specifically for smile lines, crow's feet, forehead lines, and lines around the mouth. It uses five types of hyaluronic acid, including injectable-grade hyaluronic acid, to help re-volumize the look of skin and soften the appearance of etched lines. This kind of treatment is best for people who want a no-needle option that targets visible creasing without changing the rest of their routine. It fits especially well if your main concern is localized lines rather than overall dullness or uneven tone. The tradeoff is that it is not a substitute for injectable procedures, and it will not address every sign of aging on its own. For best results, pair it with a broader anti-aging routine that includes sunscreen, moisturizer, and treatments that support collagen production and skin barrier repair.
A strong anti-aging skincare routine usually includes four basics: gentle cleansing, targeted treatment, moisturizer, and daily sunscreen. If wrinkles and expression lines are your main concern, apply a targeted treatment like Skinbetter Science InterFuse Intensive Treatment LINES morning and evening on clean, dry skin before moisturizer. It is made to focus on deeper facial lines and uses skinbetter's InterFuse delivery technology with multiple forms of hyaluronic acid to visibly plump and soften those areas. This approach works well for women who want a more clinical skincare routine without jumping straight to procedures. After your treatment step, use a moisturizer to support hydration and the skin barrier, then finish with face sunscreen during the day to help prevent further photoaging. If you have other concerns like pigmentation, acne, or sensitivity, your routine may also need a separate serum or treatment. The main limitation is that one product will not cover every aging concern, so the best routine is usually layered and consistent rather than relying on a single anti-aging product.
A targeted line treatment is made for specific facial creases, while a regular anti-aging serum or moisturizer is usually designed for broader concerns like overall hydration, texture, or early fine lines. Skinbetter Science InterFuse Intensive Treatment LINES is a targeted treatment, which means it is intended to be applied directly to areas such as smile lines, crow's feet, forehead lines, and lines around the mouth. Its focus is visible plumping and softening of deeper expression lines using five types of hyaluronic acid. This makes it a good choice for someone who already has established lines and wants more precision than a general face cream can offer. A moisturizer can help support skin hydration and barrier repair across the whole face, but it may not give the same targeted, line-focused effect. The tradeoff is that a targeted treatment is usually not enough as your only anti-aging product. Most people get the best results by using it alongside a well-rounded routine with moisturizer and sunscreen, and optionally complementary face and eye treatments if aging concerns extend beyond one area.
Yes, Skinbetter Science InterFuse Intensive Treatment LINES is designed for multiple skin types, including dry, normal, combination, and oily skin. Because it is a targeted hyaluronic acid treatment rather than a heavy cream, it can work well for people who want hydration and visible plumping in lined areas without adding a greasy feel across the whole face. That makes it especially useful for shoppers who need anti-aging skincare but still want something compatible with oilier or combination skin. For sensitive skin, the main consideration is not just skin type but skin reactivity. This product is a professional-grade treatment, so it is best introduced into a routine thoughtfully, especially if you are already using exfoliants, retinoids, or acne treatment products. Applying it to clean, dry skin before moisturizer can help support comfort and hydration. The limitation is that if your primary issue is redness, rosacea, or a compromised skin barrier, you may need to prioritize barrier repair products first and then add targeted wrinkle care once skin feels more stable.
Skinbetter Science InterFuse Intensive Treatment LINES is best for people who are starting to notice visible expression lines or already have deeper wrinkles around the eyes, forehead, mouth, or smile area. You do not need to wait for severe aging to begin using a targeted anti-aging treatment. Many people add this type of product once lines begin lingering at rest, not just during facial movement, because that is often when a more focused treatment becomes useful. It is a strong fit for shoppers who want a clinical, no-needle option that can be layered into an existing skincare routine. It is especially relevant if your main goal is to visibly plump specific lines rather than treat acne, pigmentation, or all-over dryness. Use it morning and evening on clean, dry skin before moisturizer, and wear sunscreen during the day. The tradeoff is that it is a specialized product, so if your concerns are mainly dullness, breakouts, or uneven tone, a different treatment category may be a better first step. It works best as part of a complete anti-aging routine rather than as a standalone solution.