ZO Growth Factor Serum

Use ZO Growth Factor Serum once or twice daily, depending on your skin’s tolerance and other actives in your routine. The lightweight gel formula absorbs quickly, so applying it after cleansing and before moisturizer helps deliver growth factors that support skin rejuvenation and barrier strength. Using it in the morning can help maintain hydration and support daytime skin resilience, while evening use supports repair during sleep. People with sensitive skin should start every other day or use it only at night for the first two weeks and perform a patch test. If you are on prescription topical treatments, consult your dermatologist for a personalized schedule.

You may notice improved hydration and smoother skin within a few days, while visible changes in texture and fine lines typically appear after 4 to 12 weeks of consistent use. Growth factors are protein signals that encourage cellular repair and collagen production, processes that take multiple weeks to show measurable differences. The gel base also provides immediate moisture and a plumping effect that can reduce the appearance of fine lines quickly. Results vary with baseline skin condition, consistency of use, and concurrent treatments, so expect gradual improvement rather than overnight transformation.

Yes. ZO Growth Factor Serum is formulated as a lightweight gel suitable for all skin types, including oily and acne-prone skin, and is less likely to feel heavy or contribute to pore congestion. Its focus on strengthening the skin and supporting rejuvenation helps repair barrier damage and post-inflammatory discoloration without relying on thick emollients. That said, if you have active cystic acne or are using strong prescription acne medications, introduce the serum gradually and patch test first. For best results, use it alongside non-comedogenic moisturizers and follow any acne treatment guidance from your dermatologist.

Yes, ZO Growth Factor Serum can be used with retinol and many other active treatments, but introduce combinations slowly and monitor for irritation. Growth factors support repair and collagen production, which can complement retinol’s cellular-renewal effects. Because retinol can increase sensitivity, consider alternating nights, using growth factor serum in the morning and retinol at night, or applying the growth factor first and allowing it to absorb before layering a retinoid, depending on tolerance. Avoid combining multiple strong exfoliating acids or physical irritants at the same time, and consult a dermatologist if you use prescription-strength topicals to create a safe regimen.

ZO Growth Factor Serum is distinguished by its lightweight gel texture and formulation for all skin types, designed to strengthen skin, support rejuvenation, and help protect against future signs of aging. The gel base allows rapid absorption with less residue than heavier creams, making it suitable for oily, combination, and dry skin. Its targeted approach focuses on supporting the skin barrier and promoting repair signals rather than simply providing surface hydration. That said, specific ingredient concentrations and clinical claims vary across products, so compare ingredient lists and consult product literature or a clinician if you need evidence for a particular skin concern.